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Anti-KDR antibody (1150-1230) Europäischer Partner

ArtNr STJ93087-100
Hersteller St John's Laboratory
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD antigen CD309
Similar products Vascular endothelial growth factor receptor 2
VEGFR-2
Fetal liver kinase 1
FLK-1
Kinase insert domain receptor
KDR
Protein-tyrosine kinase receptor flk-1
CD antigen CD309
Lieferbar
Storage Conditions
Store at-20°C, and avoid repeat freeze-thaw cycles.
Molecular Weight
145 kDa
Description
Rabbit polyclonal to Flk-1.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
1150-1230 aa
Tissue specificity
Detected in cornea (at protein level). Widely expressed.
Cellular localization
Cell junction Endoplasmic reticulum. Localized with RAP1A at cell-cell junctions. Colocalizes with ERN1 and XBP1 in the endoplasmic reticulum in endothelial cells in a vascular endothelial growth factor (VEGF)-dependent manner. Isoform 1: Cell membrane. Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Detected on caveolae-enriched lipid rafts at the cell surface. Is recycled from the plasma membrane to endosomes and back again. Phosphorylation triggered by VEGFA binding promotes internalization and subsequent degradation. VEGFA binding triggers internalization and translocation to the nucleus.. Isoform 2: Secreted Isoform 3: Secreted.
Clonality
Polyclonal
Protein name
Vascular endothelial growth factor receptor 2
VEGFR-2
Fetal liver kinase 1
FLK-1
Kinase insert domain receptor
KDR
Protein-tyrosine kinase receptor flk-1
CD antigen CD309
Gene symbol
KDR
Dilution range
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Note
For Research Use Only (RUO).
Immunogen Region
1150-1230 aa
Short Description
Rabbit polyclonal against Flk-1

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