Anti-SMAD3 antibody [8B5]

ArtNr	STJ97524-50
Hersteller	St John's Laboratory
Menge	50 ug
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC
Clon	8B5
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Anti-Mothers Against Decapentaplegic Homolog 3 antibody, Anti-Mad Homolog 3 antibody, Anti-Mad3 antibody, Anti-Mothers Against Dpp Homolog 3 antibody, Anti-Hmad-3 antibody, Anti-Jv15-2 antibody, Anti-Smad Family Member 3 antibody, Anti-Smad 3 antibody, Anti-Smad3 antibody, Anti-Hsmad3 antibody, Anti-SMAD3 MADH3 antibody
Similar products	Anti-Mothers Against Decapentaplegic Homolog 3 antibody Anti-Mad Homolog 3 antibody Anti-Mad3 antibody Anti-Mothers Against Dpp Homolog 3 antibody Anti-Hmad-3 antibody Anti-Jv15-2 antibody Anti-Smad Family Member 3 antibody Ant
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Storage Conditions	Store at-20°C, and avoid repeat freeze-thaw cycles.
Description	Mouse monoclonal to Smad3 (8B5).
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen	Recombinant Protein
Cellular localization	Cytoplasm Nucleus Cytoplasmic And Nuclear In The Absence Of Tgf-Beta On Tgf-Beta Stimulation Migrates To The Nucleus When Complexed With Smad4 Through The Action Of The Phosphatase Ppm1a Released From The Smad2/Smad4 Complex And Exported Out Of The Nucleus By Interaction With Ranbp1 Co-Localizes With Lemd3 At The Nucleus Inner Membrane Mapk-Mediated Phosphorylation Appears To Have No Effect On Nuclear Import Pdpk1 Prevents Its Nuclear Translocation In Response To Tgf-Beta
Clonality	Monoclonal
Protein name	Mothers Against Decapentaplegic Homolog 3 Mad Homolog 3 Mad3 Mothers Against Dpp Homolog 3 Hmad-3 Jv15-2 Smad Family Member 3 Smad 3 Smad3 Hsmad3
Gene symbol	SMAD3
Dilution range	WB 1:1000-2000 IHC 1:100-200
Note	For Research Use Only (RUO).
Short Description	Mouse monoclonal against Smad3

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Menge: 50 ug

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