Anti-AKT1 antibody

ArtNr	STJ99609-100
Hersteller	St John's Laboratory
Menge	100 ug
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha
Similar products	RAC-alpha serine/threonine-protein kinase Protein kinase B PKB Protein kinase B alpha PKB alpha Proto-oncogene c-Akt RAC-PK-alpha
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Storage Conditions	Store at-20°C, and avoid repeat freeze-thaw cycles.
Molecular Weight	55 kDa
Description	Rabbit polyclonal to Akt.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Synthesized peptide derived from human Akt.
Tissue specificity	Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
Cellular localization	Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A. Phosphorylation on Tyr-176 by TNK2 results in its localization to the cell membrane where it is targeted for further phosphorylations on Thr-308 and Ser-473 leading to its activation and the activated form translocates to the nucleus. Colocalizes with WDFY2 in intracellular vesicles.
Clonality	Polyclonal
Protein name	RAC-alpha serine/threonine-protein kinase Protein kinase B PKB Protein kinase B alpha PKB alpha Proto-oncogene c-Akt RAC-PK-alpha
Gene symbol	AKT1
Dilution range	WB 1:500-2000 ELISA 1:10000-20000
Note	For Research Use Only (RUO).
Short Description	Rabbit polyclonal against Akt

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Menge: 100 ug

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