Anti-STAT1 antibody

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Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Isotype IgG
Applikationen WB, IF
Menge 50ul
Host Rabbit
ArtNr STJ114211-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P42224
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 513-712 of human STAT1 (NP_644671. 1).
Short Description
Rabbit polyclonal against STAT1
Cellular localization
Cytoplasm
Nucleus
Translocated Into The Nucleus Upon Tyrosine Phosphorylation And Dimerization
In Response To Ifn-Gamma And Signaling By Activated Fgfr1
Fgfr2
Fgfr3 Or Fgfr4
Monomethylation At Lys-525 Is Required For Phosphorylation At Tyr-701 And Translocation Into The Nucleus
Translocates Into The Nucleus In Response To Interferon-Beta Stimulation
Molecular weight
Calculated: 83kDa/87kDa.
Dilution range
WB 1:500-1:2000 IF 1:50-1:100
Alternative names
Anti-Signal Transducer And Activator Of Transcription 1-Alpha/Beta antibody
Anti-Transcription Factor Isgf-3 Components P91/P84 antibody
Anti-STAT1 antibody
Protein name
Signal Transducer And Activator Of Transcription 1-Alpha/Beta
Transcription Factor Isgf-3 Components P91/P84
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 204,00 €
Preis: 204,00 €
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