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Anti-STAT1 antibody

Anti-STAT1 antibody

Manufacturer	St John's Laboratory
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse
Isotype	IgG
Applications	WB, IF
Amount	50ul
Host	Rabbit
Item no.	STJ114211-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	P42224
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID	6772
Gene symbol	STAT1
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 513-712 of human STAT1 (NP_644671. 1).
Short Description	Rabbit polyclonal against STAT1
Cellular localization	Cytoplasm Nucleus Translocated Into The Nucleus Upon Tyrosine Phosphorylation And Dimerization In Response To Ifn-Gamma And Signaling By Activated Fgfr1 Fgfr2 Fgfr3 Or Fgfr4 Monomethylation At Lys-525 Is Required For Phosphorylation At Tyr-701 And Translocation Into The Nucleus Translocates Into The Nucleus In Response To Interferon-Beta Stimulation
Molecular weight	Calculated: 83kDa/87kDa.
Dilution range	WB 1:500-1:2000 IF 1:50-1:100
Alternative names	Anti-Signal Transducer And Activator Of Transcription 1-Alpha/Beta antibody Anti-Transcription Factor Isgf-3 Components P91/P84 antibody Anti-STAT1 antibody
Protein name	Signal Transducer And Activator Of Transcription 1-Alpha/Beta Transcription Factor Isgf-3 Components P91/P84
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	STAT1_HUMAN

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

available

Delivery expected until 5/23/2024