Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Mouse, Rat |
Isotype |
IgG |
Applikationen |
WB |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
STJ114762-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q7L099 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-65 of human RUFY3 (NP_055776. 1). |
Short Description |
Rabbit polyclonal against RUFY3 |
Tissue specificity |
Overexpressed in gastric cancer cells and tissues (at protein level). |
Cellular localization |
CytoplasmEndomembrane SystemCell ProjectionInvadopodiumPerikaryonGrowth ConeFilopodiumLamellipodiumColocalizes With Pak1F-ActinMyosins And Integrins In Invadopodia At The Cell PeripheryColocalized With Ras-Related Rab-5 Proteins In Cytoplasmic VesiclesAccumulates In Axon Growth Cones In A F-Actin-Dependent MannerColocalized With Fscn1 And F-Actin At Filipodia And Lamellipodia Of Axonal Growth ConesColocalized With Dbn1 And F-Actin At Transitional Domain Of The Axonal Growth Cone |
Molecular weight |
Calculated: 52kDa/55kDa/64kDa/70kDa. Observed: 56kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Protein Rufy3 antibodyAnti-Run And Fyve Domain-Containing Protein 3 antibodyAnti-Rap2-Interacting Protein X antibodyAnti-Ripx antibodyAnti-Single Axon-Regulated Protein antibodyAnti-Singar antibodyAnti-RUFY3 KIAA0871 antibody |
Protein name |
Protein Rufy3Run And Fyve Domain-Containing Protein 3Rap2-Interacting Protein XRipxSingle Axon-Regulated ProteinSingar |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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