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Anti-RUFY3 antibody

Anti-RUFY3 antibody

Manufacturer	St John's Laboratory
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Mouse, Rat
Isotype	IgG
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	STJ114762-100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q7L099
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.
Gene ID	22902
Gene symbol	RUFY3
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-65 of human RUFY3 (NP_055776. 1).
Short Description	Rabbit polyclonal against RUFY3
Tissue specificity	Overexpressed in gastric cancer cells and tissues (at protein level).
Cellular localization	Cytoplasm Endomembrane System Cell Projection Invadopodium Perikaryon Growth Cone Filopodium Lamellipodium Colocalizes With Pak1 F-Actin Myosins And Integrins In Invadopodia At The Cell Periphery Colocalized With Ras-Related Rab-5 Proteins In Cytoplasmic Vesicles Accumulates In Axon Growth Cones In A F-Actin-Dependent Manner Colocalized With Fscn1 And F-Actin At Filipodia And Lamellipodia Of Axonal Growth Cones Colocalized With Dbn1 And F-Actin At Transitional Domain Of The Axonal Growth Cone
Molecular weight	Calculated: 52kDa/55kDa/64kDa/70kDa. Observed: 56kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Protein Rufy3 antibody Anti-Run And Fyve Domain-Containing Protein 3 antibody Anti-Rap2-Interacting Protein X antibody Anti-Ripx antibody Anti-Single Axon-Regulated Protein antibody Anti-Singar antibody Anti-RUFY3 KIAA0871 antibody
Protein name	Protein Rufy3 Run And Fyve Domain-Containing Protein 3 Rap2-Interacting Protein X Ripx Single Axon-Regulated Protein Singar
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	RUFY3_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

available

Delivery expected until 6/6/2024