CCL2, Recombinant, Mouse, aa24-148, His-Tag (C-C Motif Chemokine 2, AI323594, HC11, JE, MCAF, MCP-1, MCP1, Scya2, Sigje, SMC-CF)

Blue Ice

16

Supplied as a liquid in PBS, pH 7.4, 10% glycerol.

Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Source:
Recombinant protein corresponding to mouse CCL2, fused to His-tag at N-terminal expressed in E.coli.

Molecular Weight:
~16kD (146aa) (MALDI-TOF)

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MQPDAVNAPL TCCYSFTSKM IPMSRLESYK RITSSRCPKE AVVFVTKLKR EVCADPKKEW VQTYIKNLDR NQMRSEPTTL FKTASALRSS APLNVKLTRK SEANASTTFS TTTSSTSVGV TSVTVN

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.