Tyrosine-Protein Kinase BLK (BLK) Antibody

Tyrosine-Protein Kinase BLK (BLK)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development. Activation of B cells by various ligands is accompanied by activation of Blk. It has been suggested that Blk is involved in the control of B cell differentiation and proliferation. Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis. Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response.

Ascitic fluid containing 0.03% sodium azide.

BLK

Unpurified ascites.

191305