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CASP3 Antibody

CASP3 Antibody

Item no.	abx034999-100
Manufacturer	Abbexa
Amount	100 ul
Type	Antibody Primary
Applications	WB
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CASP3
Available
Description	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, 7 and 9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Antigen	CASP3
Conjugation	Unconjugated
Immunogen	Human CASP3.
Purification	Purified Mouse Monoclonal Antibody.
Storage	Aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P42574
Buffer	PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Lead Time	Shipped within 5-10 working days.
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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