Arginase 1 (ARG1) Antibody

Arginase 1 (ARG1)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Arginase 1 (ARG1) Antibody is a Rabbit Polyclonal antibody for the detection of ARG1.

Arginase-1 (Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation (PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins (PMID: 20071539).It can exsit as a homotrimer (PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control. (PMID:27117406).

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

ARG1

Purified by immunogen affinity chromatography.