Macrosialin (CD68) Antibody

Macrosialin (CD68)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Macrosialin (CD68) Antibody is a Rabbit Polyclonal antibody for the detection of CD68.

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

CD68

Purified by immunogen affinity chromatography.