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IRS-1 (phospho Ser312) Polyclonal Antibody

IRS-1 (phospho Ser312) Polyclonal Antibody

Manufacturer	Abbkine Scientific
Category	Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Adhesion Molecules Antibodies Western Blot ELISA Immunofluorescence Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	ELISA, Immunofluorescence, Western Blot
Amount	100ul
Host	Rabbit
Item no.	ABK-ABP50451-100ul
Targets	IRS1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen	Synthesized peptide derived from human IRS-1 around the phosphorylation site of S312
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	IRS1 encodes a protein (insulin receptor substrate 1) which is phosphorylated by insulin receptor tyrosine kinase. Mutations in IRS1 are associated with type II diabetes and susceptibility to insulin resistance.
Gene ID	3667
Alternative	IRS1; Insulin receptor substrate 1; IRS-1
Other info	Phospho-IRS-1 (S312) Polyclonal Antibody detects endogenous levels of IRS-1 protein only when phosphorylated at S312.
Accession	P35568

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 7/18/2024