COL8A2 Polyclonal Antibody

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Liquid solution

PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.

Gel pack with blue ice.

COL8A2 (Collagen Type VIII Alpha 2 Chain) is a Protein Coding gene. Diseases associated with COL8A2 include Corneal Dystrophy, Posterior Polymorphous 2 and Corneal Dystrophy, Fuchs Endothelial, 1. Among its related pathways are Phospholipase-C Pathway and Collagen chain trimerization. This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in COL8A2 are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.

Collagen alpha-2(VIII) chain; Endothelial collagen

P25067