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Anti-ATF2 (Thr52) Antibody

Anti-ATF2 (Thr52) Antibody

Item no.	ABC-AN1318
Manufacturer	Abcepta
Amount	100 ul
Category	Neuroscience Aging & Neurological Disorders Neural Signaling
Specific against	other
Host	Rabbit
Isotype	IgG
Alias	Activating transcription factor 2 antibody,Activating transcription factor 2 splice variant ATF2 var2 antibody,ATF 2 antibody,Atf-2 antibody,Atf2 antibody,ATF2 protein antibody,ATF2_HUMAN antibody,cAMP Response Element Binding Protein 2 antibody,cAMP response element binding protein CRE BP1 antibody,cAMP response element-binding protein CRE-BP1 antibody,cAMP responsive element binding protein 2,formerly antibody,cAMP-dependent transcription factor ATF-2 antibody,cAMP-responsive element-binding protein 2 antibody,CRE BP1 antibody,CRE-BP antibody,CREB 2 antibody,CREB-2 antibody,CREB2 antibody,CREBP1 antibody,Cyclic AMP dependent transcription factor ATF 2 antibody,Cyclic AMP-dependent transcription factor ATF-2 antibody,Cyclic AMP-responsive element-binding protein 2 antibody,D130078H02Rik antibody,D18875 antibody,HB 16 antibody,HB16 antibody,Histone acetyltransferase ATF2 antibody,MGC105211 antibody,MGC105222 antibody,MGC111558 antibody,MGC142504 antibody,mXBP antibody,MXBP protein antibody,Tg(Gzma-Klra1)7Wum antibody,TREB 7 antibody,TREB7 antibody
Available
Manufacturer - Category	Primary Antibodies; Immunology
Manufacturer - Targets	The transcription factor ATF2 is a member of the ATF/CREB family of leucine zipper proteins. In response to stress stimuli, it activates a variety of gene targets that are involved in oncogenesis, and has been correlated with maintenance of a cancer cell phenotype (Vlahopoulos et al., 2008). Inhibiting ATF2 impedes melanoma development and elicits tumor suppressor function (Bhoumik et al., 2008). To act as a tumor suppressor, ATF2 must localize at the mitochondria, and phosphorylation at Thr-52 by PKCε regulates this translocation (Lau et al., 2012).
Bio Background	The transcription factor ATF2 is a member of the ATF/CREB family of leucine zipper proteins. In response to stress stimuli, it activates a variety of gene targets that are involved in oncogenesis, and has been correlated with maintenance of a cancer cell phenotype (Vlahopoulos et al., 2008). Inhibiting ATF2 impedes melanoma development and elicits tumor suppressor function (Bhoumik et al., 2008). To act as a tumor suppressor, ATF2 must localize at the mitochondria, and phosphorylation at Thr-52 by PKC? regulates this translocation (Lau et al., 2012).
Clonality	Polyclonal
Gene Name	ATF2
Subtitle	Our Anti-ATF2 (Thr52) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is pr
Calculated Molecular Weight	54537
Formulation	Antigen Affinity Purified from Pooled Serum

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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