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Anti-MeCP2 (Ser80) Antibody

Anti-MeCP2 (Ser80) Antibody

Item no.	ABC-AN1444
Manufacturer	Abcepta
Amount	100 ul
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Epigenetics Western Blot Glial Cell Markers
Applications	WB
Specific against	Cattle (Bovine)
Host	Rabbit
Isotype	IgG
Alias	AUTSX 3 antibody,AUTSX3 antibody,DKFZp686A24160 antibody,Mbd 5 antibody,Mbd5 antibody,MECP 2 antibody,MeCP 2 protein antibody,MeCP-2 protein antibody,Mecp2 antibody,MECP2_HUMAN antibody,Methyl CpG binding protein 2 (Rett syndrome) antibody,Methyl CpG binding protein 2 antibody,Methyl-CpG-binding protein 2 antibody,MRX 16 antibody,MRX 79 antibody,MRX16 antibody,MRX79 antibody,MRXS 13 antibody,MRXS13 antibody,MRXSL antibody,PPMX antibody,RS antibody,RTS antibody,RTT antibody,WBP 10 antibody,WBP10 antibody
Available
Manufacturer - Category	Primary Antibodies; Neuroscience
Manufacturer - Targets	MECP2 (Methyl-CpG Binding Protein 2) is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair and is not influenced by sequences flanking the methyl-CpGs. MECP2 has been shown to mediate transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Defects in MECP2 are the cause of Rett syndrome (RTT). RTT is an X-linked dominant disease, it is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Recent studies have reported a new phosphorylation site at Ser-80. Phosphorylation and dephosphorylation of this site may be involved in modulating the dynamic function of MECP2 in neurons transiting between resting and active states within neural circuits that underlie behaviors. (Tao et al., 2009)
Bio Background	MECP2 (Methyl-CpG Binding Protein 2) is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair and is not influenced by sequences flanking the methyl-CpGs. MECP2 has been shown to mediate transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Defects in MECP2 are the cause of Rett syndrome (RTT). RTT is an X-linked dominant disease, it is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Recent studies have reported a new phosphorylation site at Ser-80. Phosphorylation and dephosphorylation of this site may be involved in modulating the dynamic function of MECP2 in neurons transiting between resting and active states within neural circuits that underlie behaviors. (Tao et al., 2009)
Clonality	Polyclonal
Gene Name	MECP2
Subtitle	Our Anti-MeCP2 (Ser80) phosphospecific primary antibody from PhosphoSolutions is rabbit polyclonal.
Reactivity	B
Calculated Molecular Weight	52441
Formulation	Serum

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 11/6/2025

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