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CASP6 Antibody (S257)

CASP6 Antibody (S257)

Item no.	ABC-AP1313d-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Apoptosis Western Blot
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Schmeck, B., et al., Infect. Immun. 72(9):4940-4947 (2004). Mendez, E., et al., J. Virol. 78(16):8601-8608 (2004). MacLachlan, T.K., et al., Proc. Natl. Acad. Sci. U.S.A. 99(14):9492-9497 (2002). Sordet, O., et al., Leukemia 16(8):1569-1570 (2002). LeBlanc, A., et al., J. Biol. Chem. 274(33):23426-23436 (1999).
NCBI	NP_001217.2,NP_116787.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Caspase-6,CASP-6,Apoptotic protease Mch-2,Caspase-6 subunit p18,Caspase-6 subunit p11,CASP6,MCH2
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Metabolism; Neuroscience
Manufacturer - Targets	This CASP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S257 of human CASP6.
Bio Background	CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB06896
Gene Name	CASP6
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B, Rat
Calculated Molecular Weight	33310
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 11/6/2025

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