Comparison

PTPa Antibody (S180)

Item no. ABC-AP8412D
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against other
Host Rabbit
Isotype IgG
Citations Deloukas, P., et al., Nature 414(6866):865-871 (2001).
Kaplan, R., et al., Proc. Natl. Acad. Sci. U.S.A. 87(18):7000-7004 (1990).
Krueger, N.X., et al., EMBO J. 9(10):3241-3252 (1990).
Sap, J., et al., Proc. Natl. Acad. Sci. U.S.A. 87(16):6112-6116 (1990).
Jirik, F.R., et al., FEBS Lett. 273 (1-2), 239-242 (1990).
NCBI NP_002827.1,NP_543030.1,NP_543031.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Receptor-type tyrosine-protein phosphatase alpha,Protein-tyrosine phosphatase alpha,R-PTP-alpha,PTPRA,PTPA,PTPRL2
Available
Manufacturer - Category
Primary Antibodies; Signal Transduction
Manufacturer - Targets
This PTPa antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from human PTPa.
Bio Background
PTPa is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB36335
Gene Name
PTPRA
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
M, Rat
Calculated Molecular Weight
90719
Antigen Source
HUMAN
Antigen Region
169-196
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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