AG490

Item no.	M1646-50mg
Manufacturer	AbMole
CASRN	133550-30-8
Amount	50mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	1
Citations	AG490 Promotes HIF-1alpha Accumulation by Inhibiting Its Hydroxylation. Fernandez-Sanchez, et al . Curr Med Chem. 2012 Aug 1,19(23):4014-23. PMID: 22709000 . Tyrphostin AG490 Agent Modestly but Significantly Prevents Onset of Type 1 in NOD Mouse, Implication of Immunologic and Metabolic Effects of a Jak-Stat Pathway Inhibitor. Davoodi-Semiromi, et al . J Clin Immunol. 2012 Jun 4. PMID: 22661285 .
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Tyrphostin AG490
Similar products	AG490, Tyrphostin AG490
Available
Target Information	JAK
Molecular Weight	294, 3
Solubility	DMSO ≥45 mg/mL
Bioactivity information	AG490 (Tyrphostin AG490) is a selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively).

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M1646-50mg-safety-datasheet.pdf