GSK1120212 (Trametinib)

Item no.	M1759-10mg
Manufacturer	AbMole
CASRN	871700-17-3
Amount	10mg
Category	Oncology Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Breast Cancer
Type	Inhibitors
Specific against	other
Purity	0,9981
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	JTP-74057, GSK212
Similar products	GSK1120212, JTP-74057, GSK212
Available
Target Information	MEK
Molecular Weight	615, 39
Solubility	DMSO 30 mg/mL
Bioactivity information	Trametinib (GSK1120212; Jtp-74057) is an orally effective MEK inhibitor with IC50 of 2 nM against MEK1 and MEK2, respectively. Trametinib can activate autophagy and induce apoptosis.

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M1759-10mg-safety-datasheet.pdf