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AZD5438

AZD5438

Item no.	M1810-200mg
Manufacturer	AbMole
CASRN	602306-29-6
Amount	200mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>99%
Citations	AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts. Byth KF, et al . Mol Cancer Ther. 2009 Jul,8(7):1856-66. PMID: 19509270 . A phase I pharmacodynamic study of the effects of the cyclin-dependent kinase-inhibitor AZD5438 on cell cycle markers within the buccal mucosa, plucked scalp hairs and peripheral blood mononucleocytes of healthy male volunteers. Camidge DR, et al . Cancer Chemother Pharmacol. 2007 Sep,60(4):479-88. PMID: 17143601 .
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AZD 5438
Similar products	AZD5438, AZD 5438
Available
Target Information	CDK
Molecular Weight	371, 46
Solubility	DMSO 64 mg/mL; Ethanol 54 mg/mL
Bioactivity information	AZD5438 is a novel, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively).

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M1810-200mg-safety-datasheet.pdf