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OSI-906

OSI-906

Item no.	M1821-1g
Manufacturer	AbMole
CASRN	867160-71-2
Amount	1g
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Pancreatic Cancer
Type	Inhibitors
Specific against	other
Purity	>99%
Citations	Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-1 receptor and insulin receptor. Mulvihill MJ, et al . Future Med Chem. 2009 Sep,1(6):1153-71. PMID: 21425998 .
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Linsitinib
Similar products	OSI-906, Linsitinib
Available
Target Information	IGF-1R
Molecular Weight	421, 49
Solubility	DMSO 62 mg/mL
Bioactivity information	OSI-906 (Linsitinib) is a potent, selective, dual ATP-competitive tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) with IC50 values of 35 nM and 75 nM respectively.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M1821-1g-safety-datasheet.pdf