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Tandutinib

Tandutinib

Item no.	M1828-500mg
Manufacturer	AbMole
CASRN	387867-13-2
Amount	500mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	1
Citations	HPLC-DAD protein kinase inhibitor analysis in human serum. Dziadosz, et al . J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Apr 15,893-894:77-81. PMID: 22425385 . Preclinical testing of tandutinib in a transgenic medulloblastoma mouse model. Ohshima-Hosoyama, et al . J Pediatr Hematol Oncol. 2012 Mar,34(2):116-21. PMID: 22146535 . Multidimensional profiling of CSF1R screening hits and inhibitors: assessing cellular activity, target residence time, and selectivity in a higher throughput way. Uitdehaag, et al . J Biomol Screen. 2011 Oct,16(9):1007-17. PMID: 21873591 . Accelerated disease progression in prostate cancer and bone metastases with platelet-derived growth factor receptor inhibition: observations with tandutinib. Mathew, et al . Cancer Chemother Pharmacol. 2011 Oct,68(4):889-96. PMID: 21290244 . Neuromuscular junction toxicity with tandutinib induces a myasthenic-like syndrome. Lehky, et al . Neurology. 2011 Jan 18,76(3):236-41. PMID: 21242491 .
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MLN518, CT53518
Similar products	Tandutinib, MLN518, CT53518
Available
Molecular Weight	562, 7
Solubility	Ethanol
Bioactivity information	Tandutinib (MLN518), previously known as CT53518, is an orally active multitargeted tyrosine kinase inhibitor of FLT3, PDGFR and c-Kit.

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M1828-500mg-safety-datasheet.pdf