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Cyclosporine A

Cyclosporine A

Item no.	M1831-5g
Manufacturer	AbMole
CASRN	59865-13-3
Amount	5g
Category	Food Safety Allergenes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	1
Citations	The protective effects of omega 3 fatty acids and sesame oil against cyclosporine A-induced nephrotoxicity. Goksu Erol, et al . Drug Chem Toxicol. 2012 Sep 6. PMID: 22950701 .
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Cyclosporine
Similar products	Cyclosporine A, Cyclosporine
Available
Target Information	Immunology/Inflammation
Molecular Weight	1202, 61
Solubility	DMSO ≥ 45 mg/mL
Bioactivity information	Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.

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M1831-5g-safety-datasheet.pdf