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LDN-193189 dihydrochloride

LDN-193189 dihydrochloride

Item no.	M2805-10mg
Manufacturer	AbMole
CASRN	1435934-00-1
Amount	10mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	DM-3189 dihydrochloride
Available
Molecular Weight	479, 4
Solubility	Water 11 mg/mL; DMSO 8 mg/mL (ultrasonic and warming)
Bioactivity information	LDN-193189 dihydrochloride is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, 200-fold selectivity for BMP versus TGF-β.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M2805-10mg-safety-datasheet.pdf