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Alexidine dihydrochloride

Alexidine dihydrochloride

Item no.	M3180-1g
Manufacturer	AbMole
CASRN	22573-93-9
Amount	1g
Category	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer Pancreatic Cancer
Type	Inhibitors
Specific against	other
Purity	>99%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Bioactivity	Alexidine dihydrochloride is a potent and selective PTPMT1 (Protein Tyrosine Phosphatase Localized to the Mitochondrion 1) inhibitor (IC50 = 1.08 uM in vitro). It binds to lipopolysaccharide and lipoteichoic acid and inhibits fungal phospholipase B (IC50 ca. 250 nM). Alexidine increases insulin secretion by isolated rat pancreatic islets. Alexidine induces apoptosis in cancer cell lines (ED50 = 1.8-2.6 uM).
Chemical name	2, ?4, ?11, ?13-?Tetraazatetradecaned?iimidamide, N, ?N''-?bis(2-?ethylhexyl)?-?3, ?12-?diimino-
MW	581, 71
Signaling Pathways	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1g

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Delivery expected until 1/15/2026

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