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Flavopiridol hydrochloride

Flavopiridol hydrochloride

Item no.	M3483-10mg
Manufacturer	AbMole
CASRN	131740-09-5
Amount	10mg
Category	Oncology Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	>98.5%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NSC 649890 HCl
Available
Target Information	CDK
Molecular Weight	438, 3
Solubility	Water 20 mg/mL; DMSO 22 mg/mL
Bioactivity information	Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA.

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M3483-10mg-safety-datasheet.pdf