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K145 hydrochloride

K145 hydrochloride

Item no.	M3719-10mg
Manufacturer	AbMole
CASRN	1449240-68-9
Amount	10mg
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	>99%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SphK2 inhibitor
Available
Target Information	SPHK
Molecular Weight	384, 92
Solubility	Water 90 mg/mL; DMSO 40 mg/mL
Bioactivity information	K145 Hydrochloride is a selective, substrate competitive and oral inhibitor of SphK2, IC50 4.3 µM and Ki 6.4 µM. K145 hydrochloride has no activity against SphK1 and other protein kinases. K145 Hydrochloride induces apoptosis and has strong anti-tumor activity.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M3719-10mg-safety-datasheet.pdf