EED226

Item no.	M5243-10mg
Manufacturer	AbMole
CASRN	2083627-02-3
Amount	10mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	>98%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Molecular Weight	369, 4
Solubility	73 mg/mL in DMSO
Bioactivity information	EED226 is an effective, selective and orally active Polycomb reactive complex 2 (PRC2) inhibitor. When h3k27me0 peptide is used as substrate, ic50=23.4 nm; With mononucleosome as substrate, ic50=53.5 nm. It is a first in class, effective, orally bioavailable inhibitor of embryonic ectodermal development (EED) with strong anticancer effect.

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M5243-10mg-safety-datasheet.pdf