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Mivebresib

Mivebresib

Item no.	M5258-2mg
Manufacturer	AbMole
CASRN	1445993-26-9
Amount	2mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	0,9993
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ABBV-075
Available
Target Information	Epigenetic Reader Domain
Molecular Weight	459, 47
Solubility	85 mg/mL in DMSO
Bioactivity information	Mivebresib(ABBV-075) is a novel BET family bromodomain inhibitor. It binds bromodomains of BRD2/4/T with similar affinities (Ki of 1-2.2 nM) and highly selective for 18 bromodomain proteins tested (Kd > 1 μM; more than 600-fold selectivity vs. BRD4)

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M5258-2mg-safety-datasheet.pdf