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Nazartinib

Nazartinib

Item no.	M5275-5mg
Manufacturer	AbMole
CASRN	1508250-71-2
Amount	5mg
Category	Oncology Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Hepatic Cancer
Type	Inhibitors
Specific against	other
Purity	>99.0%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	EGF816, NVS-816
Available
Molecular Weight	495, 02
Solubility	99 mg/mL in DMSO
Bioactivity information	Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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M5275-5mg-safety-datasheet.pdf