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Crizotinib hydrochloride

Crizotinib hydrochloride

Item no.	M5320-50mg
Manufacturer	AbMole
CASRN	1415560-69-8
Amount	50mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Lymphatic System Cancer
Type	Inhibitors
Specific against	other
Purity	>99.0%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PF-02341066 hydrochloride
Available
Molecular Weight	486, 8
Solubility	≥ 4.6 mg/mL in DMSO
Bioactivity information	Crizotinib is inhibitor of the c-Met kinase and the NPM-ALK. Crizotinib inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM). Crizotinib is useful in treatment of anaplastic large-cell lymphoma.

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M5320-50mg-safety-datasheet.pdf