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Motesanib

Motesanib

Item no.	M5329-50mg
Manufacturer	AbMole
CASRN	453562-69-1
Amount	50mg
Category	Oncology Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Bladder Cancer
Type	Inhibitors
Specific against	other
Purity	>99.0%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AMG 706
Available
Molecular Weight	373, 45
Solubility	≥ 30 mg/mL in DMSO
Bioactivity information	Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.

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M5329-50mg-safety-datasheet.pdf