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Floxuridine

Floxuridine

Item no.	M5648-100mg
Manufacturer	AbMole
CASRN	50-91-9
Amount	100mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer
Type	Inhibitors
Specific against	other
Purity	0,9992
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Deoxyfluorouridine; FDUR; NSC 27640
Available
Target Information	DNA/RNA Synthesis
Molecular Weight	246, 19
Solubility	DMSO 100 mg/mL; Water ≥ 30 mg/mL
Bioactivity information	Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses.

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M5648-100mg-safety-datasheet.pdf