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Napabucasin (BBI608)

Napabucasin (BBI608)

Item no.	M5807-10mg
Manufacturer	AbMole
CASRN	83280-65-3
Amount	10mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Purity	0,9986
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BBI608; BB608
Available
Target Information	STAT
Molecular Weight	240, 21
Solubility	DMSO 4 mg/mL
Bioactivity information	Napabucasin (BBI608) is a first-in-class, orally active inhibitor of Stat3 that blocks stem cell activity in cancer cells by targeting the signal transducer and activator of transcription 3 pathway. Napabucasin inhibits cell proliferation of U87MG tumor xenografts in mice.

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M5807-10mg-safety-datasheet.pdf