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Iberdomide

Iberdomide

Item no.	M6072-10mg
Manufacturer	AbMole
CASRN	1323403-33-3
Amount	10mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lymphatic System Cancer
Type	Inhibitors
Specific against	other
Purity	>99%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CC220; CC 220; CC-220
Available
Target Information	Others
Molecular Weight	449, 5
Solubility	30 mg/mL in DMSO
Bioactivity information	Iberdomide (CC-220) is an orally effective cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 for cereblon binding affinity of approximately 150 nM. Iberdomide (CC-220) binds CRBN with higher affinity than lenalidomide and pomalidomide and has enhanced degradation of IKZF1 and IKZF3 with enhanced degradation.

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M6072-10mg-safety-datasheet.pdf