OptimAb Lymphatic Endothelial Marker , Monoclonal Antibody, purified

Blue ice

M2A oncofetal antigen (also called Lymphatic Endothelial Marker) is an O-linked sialoglycoprotein (40 kDa) expressed on the cell membrane of lymphatic endothelium, fetal gonocytes and certain germ cell tumor cell lines. Clone D2-40 targets the M2A antigen, and no reactivity is observed onCancer cell lines of human breast, prostate, melanoma, cervix, colon, pharynx, brain and bone marrow. In recent studies, clone D2-40 (D240) has shown staining in lymphatic channel endothelium but not in the adjacent capillary. This monoclonal Ab is used for the qualitative identification of Lymphatic Endothelial Marker in human biological samples using immunohistochemistry (IHC) methods. The clinical interpretation of any staining or its absence should be complemented by morphological studies and proper controls and should be evaluated within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.