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HCV NS3/4A protease genotype 1b, recombinant - 10 µg

HCV NS3/4A protease genotype 1b, recombinant - 10 µg

Item no.	AS-61017-10
Manufacturer	AnaSpec
Amount	10 ug
Category	Other Assays & Kits Other Kits
Type	Assay-Kit
Format	In solution
Specific against	other
Host	E.coli
Conjugate/Tag	Unconjugated
Purity	≥95% by SDS-PAGE
Dry ice	Yes
Citations	1. R. Bartenschlager, R. et al. J.Virol. 67, 3835-3844 (1993).2. Eckart, MR. et al. Biochem.Biophys.Res.Commun. 192, 399-406 (1993).3. Landro, JA. et al. Biochemistry 36, 9340-9348 (1997).4. Kim, JL. et al. Cell 87, 343-355 (1996).5. Love, RA. et al. Cell 87, 331-342 (1996).
ECLASS 10.1	32161090
ECLASS 11.0	32161090
UNSPSC	41116126
Shipping Condition	Dry ice
Available
Manufacturer - Type	Catalog recombinant
Manufacturer - Applications	Protease activity; FRET
Manufacturer - Category	Proteins
Manufacturer - Targets	Hepatitis C Virus (HCV)
Manufacturer - Host	E.coli
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	22.7 kDa
Description	The NS3 protease of hepatitis C virus (HCV) is responsible for the cleavage at the NS3/NS4A, NS4A/NS4B, NS4B/NS5A, and NS5A/NS5B sites of the nonstructural protein. It is essential for viral replication and the formation of infectious viral particles, and thus has been considered as one of the most attractive targets for anti-HCV therapy. Recombinant HCV NS3/4A protease is highly active and can be used with SensoLyte 490 or 520 HCV Protease Assay Kits (Cat# 71126, 71145) to screen for anti-HCV protease drugs.
Product Group	QB1A2Z
Research Area	Immunology and Infectious disease / In solution
GTIN	5400535155704
Concentration	lot dependent
Storage Buffer	20 mM Tris-HCl, pH 8.0, 20% Glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA.
Unit Definition	One unit of protease hydrolyzes 1 picomole of 5-FAM/QXL™ FRET substrate per minute at pH 7.5 at 25°C.
Specicifity	recombinant HCV NS3/4A protease (genotype 1b, strain: HC-J4; NCBI Accession: AF054247)
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 9/25/2025

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