Comparison

HIV-1 protease, recombinant

Item no. AS-72028-5
Manufacturer AnaSpec
Amount 5 ug
Category
Type Assay-Kit
Format Liquid
Specific against other
Host E.coli
Conjugate/Tag Unconjugated
Purity ≥95% by SDS-PAGE
Dry ice Yes
Citations 1. Seelmeier, S. et al. Proc. Natl. Acad. Sci.USA. 85, 6612 (1988).2. Schneider, J. and SB. Kent, Cell 54, 363 (1988).
ECLASS 10.1 32161090
ECLASS 11.0 32161090
UNSPSC 41116126
Alias HIV1P,HIV-1 PR
Shipping Condition Dry ice
Available
Manufacturer - Type
Catalog recombinant
Manufacturer - Applications
FRET; Protease activity
Manufacturer - Category
Catalog Recombinant Proteins / Catalog Recombinant / Proteins
Manufacturer - Targets
Human Immunodeficiency Virus 1 (HIV1)
Shipping Temperature
Dry Ice
Storage Conditions
Store at -80°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
12 kDa
Manufacturer - Research Area
Immunology and Infectious disease / Virology
Description
The 10~12 kDa aspartic protease of human immunodeficiency virus-1 (HIV-1), active only when it forms a homodimer, is required for the post-translational cleavage of the precursor polyproteins, Gag, Gag-Pol, Pol, and Nef. Since the cleavages of precursors are essential for the maturation of HIV infectious particles, this protease is one of the key targets for developing anti-AIDS drugs
Concentration
0.2 mg/ml
Unit Definition
One unit of protease hydrolyzes 1 picomole of the DABCYL/EDANS substrate in SensoLyte™ 490 HIV Protease Assay Kits (AnaSpec Cat# 71127) per min at pH 4.7 at 25°C.
Manufacturer - Specificity
Recombinant HIV-1 protease (wild type, NCBI accession: NC_001802) containing 99 amino acids
Post Synthesis Coupling
No
Usage
Research use
UNSPSC
12352202
GTIN
5400535132460

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 ug
Available: In stock
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