Comparison

SensoLyte® Rh110 DPPIV Assay Kit *Fluorimetric* - 1 kit

Item no. AS-72196
Manufacturer AnaSpec
Amount 1 kit
Category
Type Assay-Kit
Specific against other
Host Baculovirus-Infected Insect Cells
Conjugate/Tag Unconjugated
Dry ice Yes
ECLASS 10.1 32161090
ECLASS 11.0 32161090
UNSPSC 41116126
Shipping Condition Dry ice
Available
Manufacturer - Applications
FRET; Protease activity
Manufacturer - Category
Assay Kits
Manufacturer - Targets
Dipeptidylaminopeptidase (DPPIV)
Manufacturer - Host
Baculovirus-Infected Insect Cells
Manufacturer - Host
High 5 cells (baculovirus)-derived
Shipping Temperature
Dry Ice
Storage Conditions
Store component C at -80°C. Store all other components at -20°C. Protect components A and B from light and moisture.
Description
DPPIV is a widely distributed serine protease that cleaves two amino acids from small peptides containing alanine or proline in the second position of the N-terminus of the peptide. DPPIV activity is especially critical for inactivation of GLP-1, a potent antihyperglycemic hormone, inducing glucose-dependent stimulation of insulin secretion. DPPIV inhibitors provide a potent treatment for type 2 diabetes prolonging the activity of GLP-1 and improving insulin secretion and blood glucose control regulation. The SensoLyte Rh110 DPPIV Assay Kit provides a convenient method for high throughput screening of DPPIV inhibitors and for continuous assay of DPPIV activity utilizing a fluorogenic peptide. Upon enzyme cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=490/520 nm. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from reaction components. Kit size: 100 assays.
Product Group
NA1ZZZ
Research Area
Peptide & Protein Analysis; Cell & Tissue Biology; Diabetes/Metabolism / 0
Absorbtion (nm)
490
Emission (nm)
520
GTIN
5400535174101
Detection Method
Fluorescent
Usage
Research use
UNSPSC
41105331

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 kit
Available: In stock
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