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MMP-13 (Catalytic Domain), human recombinant

MMP-13 (Catalytic Domain), human recombinant

Item no.	AS-72257
Manufacturer	AnaSpec
Amount	1 ug
Category	Other Assays & Kits Other Kits
Type	Assay-Kit
Format	Liquid
Specific against	other
Host	E.coli
Conjugate/Tag	Unconjugated
Purity	≥95% by SDS-PAGE
Dry ice	Yes
ECLASS 10.1	32161090
ECLASS 11.0	32161090
UNSPSC	41116126
Alias	MMP-13,MMP 13 catlytic domain,Matrix metalloproteinase 13 caalytic domain,CLG3,MANDP1,MDST
Shipping Condition	Dry ice
Available
Manufacturer - Type	Catalog recombinant
Manufacturer - Applications	FRET; Protease activity
Manufacturer - Category	Catalog Recombinant Proteins / Catalog Recombinant / Proteins
Manufacturer - Targets	Matrix Metalloproteinase (MMP), MMP-13
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	20.4 kDa
Manufacturer - Research Area	Adhesion & Extracellular Matrix; Cancer & Apoptosis / Tissue Remodeling/MMPs; Oncogenesis
Description	The matrix metalloproteinases (MMPs) constitute a family of zinc-dependent endopeptidases that function within the extracellular matrix. These enzymes are responsible for the breakdown of connective tissues and are important in bone remodeling, menstrual cycle and the repair of tissue damage. MMP-13 (collagenase-3), is a member of the MMP family of extracellular proteases. Targets of MMP-13 include collagen, gelatin, aggracan, plasminogen and CXCL12. The native MMP-13 is secreted as a 60-kDa proenzyme, and activated by cleavage to a mature 48-kDa MMP-13. - The sequence (Accession # 1EUB_A) corresponding to the catalytic domain (aa 104-274 aa) of human MMP-13 was expressed with 6-his tag in E. coli. The molecular weight of the recombinant Human MMP-13 catalytic Domain is 20.5 kDa.
Purification Method	Purified
Concentration	10 µg/ml
Storage Buffer	0.1M Tris, pH 7.5, 0.1M NaCl, 10 mM CaCl2, 0.05% Brij 35, 2mM sodium azide, 1 mg/mL BSA.
Manufacturer - Specificity	Catalytic domain (aa 104-274 aa) of human MMP-13
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535176327

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-72257-safety-datasheet.pdf