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Calcitonin Gene Related Peptide, CGRP (alpha), human

Calcitonin Gene Related Peptide, CGRP (alpha), human

Item no.	AS-20681
Manufacturer	AnaSpec
CASRN	90954-53-3
Amount	0.5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Cell Biology Cell Status Necrosis Peptides By Organ Thyroid Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge: 2-7)
Citations	Ref: Nimmagadda D. GS. Indian J. Pharmacol. 36, 277 (2004); Feuerstein, G. et al. Can. J. Physiol. Pharmacol. 73, 1070 (1995).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (Disulfide bridge: 2-7)
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Calcitonin Gene Related Peptide (CGRP)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	3789.6
Manufacturer - Research Area	Cardiovascular Research; Neuroscience; Cell Signaling / Vasoconstriction/Vasodilation; Neuropeptides; GPCR
Description	Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide produced by tissue specific processing of the calcitonin gene and is the major product in neural tissues. CGRP is released by motor neurons where it exerts both short and long term effects on skeletal muscle fibers. In addition, sensory neurons release CGRP to the surrounding vasculature where it is partly responsible for local vasodilation following muscle contraction. CGRP acts through G protein-coupled receptors whose presence and changes in function modulate the peptide's effects in various tissues.
Sequence One-Letter Code	ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (Disulfide bridge: 2-7)
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535054052

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-20681-safety-datasheet.pdf