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Luteinizing Hormone-Releasing Hormone (LH-RH), human

Luteinizing Hormone-Releasing Hormone (LH-RH), human

Item no.	AS-20782
Manufacturer	AnaSpec
CASRN	33515-09-2
Amount	25 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Citations	Kiss, J. and B. Halasz, Neurosci 14, 69 (1985); Zheng, L. et al. Neurosci 46, 407 (1992); Collado, B. et al. Intl J Oncol 24, 725 (2004); Hoffman, G. et al. Brain Res 2005 Aug 5; [Epub ahead of print]; Wang, V. et al. Am J Obstet Gynecol 160, 984 (1989).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Pyr-HWSYGLRPG-NH2
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Luteinizing Hormone-Releasing Hormone (LH-RH)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	1182.4
Manufacturer - Research Area	Hormones / Hypothalamo-Pituitary (HPA) Axis
Description	Luteinizing Hormone-Releasing Hormone (LHRH), also known as GnRH or FSH-RH, is a hypothalamic hormone that controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary gland and promotes mating behavior. It stimulates the secretion of gonadotropins after its interaction with specific G-protein-coupled receptors that are present in plasma membranes of pituitary gonadotrophs. In addition to hypophysiotropic effect, it also plays a autocrine/paracrine role in peripheral organs such as prostate, breast and ovary. LHRH is not only a neurohormone but may also function as a neurotransmitter or neuromodulator. It also has a role in angiogenesis, cell proliferation, and tumor metastasis.
Sequence One-Letter Code	Pyr-HWSYGLRPG-NH2
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535053840

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AS-20782-safety-datasheet.pdf