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Glucagon (1-29), bovine, human, rat, porcine

Glucagon (1-29), bovine, human, rat, porcine

Item no.	AS-22457
Manufacturer	AnaSpec
CASRN	16941-32-5
Amount	1 mg
Category	Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
Citations	O'Harte. FP. et. al. Mol Cell Endocrinol 381, 26 (2013), doi: 10.1016/j.mce.2013.07.014Drucker DJ. Endocrinology: Adult and Pediatric (7th Ed.) 1, 586 (2016), doi:10.1016/B978-0-323-18907-1.00034-2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Glucagon
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	3483
Manufacturer - Research Area	Diabetes/Metabolism; Hormones; Cell Signaling / Glucagon; Pancreas; GPCR
Description	Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.
Sequence One-Letter Code	HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535046804

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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AS-22457-safety-datasheet.pdf