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ß-Secretase Inhibitor 1

ß-Secretase Inhibitor 1

Item no.	AS-23958
Manufacturer	AnaSpec
CASRN	350228-37-4
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH
Citations	Ref: Sinha, S. et al. Nature 402, 537 (1999).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KTEEISEVN-Sta-VAEF (Sta = statine)
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Protease activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Beta-Secretase
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	1652
Manufacturer - Research Area	Neuroscience; Cell Signaling / Alzheimer's Disease ; Enzyme Substrates & Inhibitors
Description	ß-Secretase (BACE1) is a key enzyme involved in the production of Aß peptides found in extracellular amyloid plaques of Alzheimer’s disease (AD). The enzyme has been implicated as an excellent target for anti-amyloid therapy of AD. This statine-based substrate analog, beta-secretase inhibitor P10–P4’ statV, is used in the inhibition of beta-secretase activity from homogenized wild-type mouse cortices and from BACE-purified from human brain.
Sequence One-Letter Code	KTEEISEVN-Sta-VAEF (Sta = statine)
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535041236

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-23958-safety-datasheet.pdf