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390 MMP Substrate XIII, NFF-3 - 1 mg

390 MMP Substrate XIII, NFF-3 - 1 mg

Item no.	AS-27114
Manufacturer	AnaSpec
Amount	1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Biotin
Purity	Peak Area by HPLC ≥95%
Sequence	Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2
Citations	Ref: Bremer, C. et al. Acad. Radiol. 9 Suppl 2, S314 (2002); Nagase, H. et al. J. Biol. Chem. 269, 20952 (1994).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mca-RPKPVE-Nva-WR-K(Dnp)-NH2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	FRET; Protease activity
Manufacturer - Category	Peptides
Manufacturer - Targets	Matrix Metalloproteinase (MMP)
Manufacturer - Conjugate / Tag	MCA-Dnp
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	1675.9
Description	NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218, 000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10, 100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2. It is one of the few synthetic substrates selectively hydrolyzed by certain members of the MMP family and thus has important applications for the differentiation of MMP-3 activity from that of other MMPs. Abs/Em = 325/393 nm.
Product Group	LB1A1Z
Research Area	Adhesion & Extracellular Matrix; Cancer & Apoptosis; Cell Signaling / Lyophilized
Absorbtion (nm)	325
Emission (nm)	393
Sequence One-Letter Code	Mca-RPKPVE-Nva-WR-K(Dnp)-NH2
GTIN	5400535026844
Detection Method	Fluorescent
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-27114-safety-datasheet.pdf