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MBP, MAPK Substrate [APRTPGGRR] - 5 mg

MBP, MAPK Substrate [APRTPGGRR] - 5 mg

Item no.	AS-27168
Manufacturer	AnaSpec
Amount	5 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	H-Ala-Pro-Arg-Thr-Pro-Gly-Gly-Arg-Arg-OH
Citations	Ref: Clark-Lewis, I. et al. J. Biol. Chem. 266, 15180 (1991); Nam, H. et al. J. Chromatogr A. 976, 79 ( 2002); Sommer, F. et al. Int. J. Impot. Res. 14, 217 (2002); Lents, NH. et al. Ann. N.Y. Acad. Sci. 973, 265 (2002); Kameshita, I. et al. J. Biochem. (Tokyo) 122, 168 (1997); Daeipour, M. et. al. J. Immunol. 150, 4743 (1993); Song, SJ. Neurosci. 18, 4119 (1998); Gerthoffer, W. et al. J. Physiol. 495, 597 (1996).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	APRTPGGRR
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	Enzyme activity
Manufacturer - Category	Peptides
Manufacturer - Targets	MAP Kinase
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	967.1
Description	The sequence APRTPGGRR contains a native sequence derived from bovine myelin basic protein amino acids 95-98 (PRTP). The rest of the sequence is not derived from a native sequence, but is a synthetic construct. This substrate is specific for MAP kinases: p44MAPK [extracellular signal-regulated kinase 1 (ERK1)] and p42MAPK (ERK2). It contains the consensus sequence Pro-X-(Ser/Thr)-Pro that is recognized by MAP kinase. This peptide is the most efficient substrate for phosphorylation reaction by ERK. The substrate is phosphorylated by kinases on threonine 97 and can also be phosphorylated by MAPK p38.
Product Group	LB1A1Z
Research Area	Cell Signaling / Lyophilized
Sequence One-Letter Code	APRTPGGRR
GTIN	5400535026479
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-27168-safety-datasheet.pdf