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EGF Receptor Substrate 2 [DADE-pY-LIPQQG], 5-FAM labeled

EGF Receptor Substrate 2 [DADE-pY-LIPQQG], 5-FAM labeled

Item no.	AS-29971-5
Manufacturer	AnaSpec
Amount	5 mg
Category	Oncology Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Adenocarcinoma Astrocytoma Peptides By Organ Bladder Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	5-FAM-Asp-Ala-Asp-Glu-pTyr-Leu-Ile-Pro-Gln-Gln-Gly-OH
Citations	Ref: Ukkola, O. and MJ. Santaniemi, Intern. Med. 251, 467 (2002); Sarmiento, M. et al. J. Biol. Chem. 273, 26368 (1998); Zhang, ZY. et al. Anal. Biochem. 211, 7 (1993).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	5-FAM-DADE-pY-LIPQQG
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Enzyme activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	EGFR, Tyrosine Phosphatase 1B
Manufacturer - Conjugate / Tag	Fluorescent dyes: FAM
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	1686.7
Manufacturer - Research Area	Cell Signaling / Kinases, Substrates & Inhibitors
Description	The labeled phosphopeptide is an excellent substrate for mammalian protein tyrosine phosphatase 1B (Km = 3.9 µM) and Yersinia PTP. The sequence is derived from an autophosphorylation site (Tyr992) of EGFR. The labeled peptide is used to assay PTB based on marked fluorescence increase upon the removal of the phosphate group (Em = 305 nm and Ex = 282 nm)
Absorbtion (nm)	282
Emission (nm)	305
Sequence One-Letter Code	5-FAM-DADE-pY-LIPQQG
Detection Method	Fluorescent
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535020910

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-29971-5-safety-datasheet.pdf