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VEGFR2/KDR Antagonist

VEGFR2/KDR Antagonist

Item no.	AS-60628
Manufacturer	AnaSpec
Amount	1 mg
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma Peptides By Organ Bladder Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Ala-Thr-Trp-Leu-Pro-Pro-Arg-OH
Citations	Ref: Renno, R. et al. Invest. Ophthalmol. Vis. Sci. 43, 3977 (2002); Brekken, R. et al. Cancer Res. 60, 5117 (2000); Jia, H. et al. J. Biol. Chem. 279, 36148 (2004); Ye, F. Gynecol. Oncol. 94, 125 (2004); Bin?truy-Tournaire, R. et al. EMBO J. 19, 1525 (2000).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ATWLPPR
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Vascular Endothelial Growth Factor (VEGF)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	840
Manufacturer - Research Area	Cancer & Apoptosis; Cardiovascular Research / Oncogenesis; Angiogenesis
Description	This peptide is a specific VEGFR2/KDR heptapeptide antagonist, it binds VEGFR2 (KDR/flk), completely inhibiting VEGF binding to KDR and preventing VEGF-induced angiogenesis in-vivo. It specifically inhibits human endothelial cell proliferation in-vitro and totally abolishes VEGF-induced angiogenesis in-vivo.
Sequence One-Letter Code	ATWLPPR
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535157340

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-60628-safety-datasheet.pdf