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Calpain Inhibitor Peptide, B27-WT

Calpain Inhibitor Peptide, B27-WT

Item no.	AS-60844
Manufacturer	AnaSpec
CASRN	128578-18-7
Amount	0.5 mg
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Cell Biology Cell Status Apoptosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	H-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-OH
Citations	Ref: Betts, R. et al. J. Biol. Chem. 278, 7800 (2003); Maki, M. et al. J. Biol. Chem. 264, 18866 (1989); R. Betts and J. Anagli, Biochem. 43, 2596 (2004); Kawasaki, H. et al. J. Biochem. (Tokyo) 106, 274 (1989); Mairhofer, M. et al. Blood 100, 897 (2002).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DPMSSTYIEELGKREVTIPPKYRELLA
Shipping Condition	Room temperature
Available
Manufacturer - Applications	Enzyme activity
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Calpain
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	3136.8
Manufacturer - Research Area	Cell Signaling; Cancer & Apoptosis / Enzyme Substrates & Inhibitors; Oncogenesis
Description	Calpains are a family of intracellular Ca2+ dependent cysteine proteases. They respond to Ca2+ signals by cleaving many specific proteins, thereby irreversibly modifying their function(s). They are implicated in a variety of Ca2+ regulated cellular processes as well as various pathological phenomena, such as ischemic injury, muscular dystrophy, diabetes, cataract, atherosclerosis, Alzheimer’s disease, and cancer. Calpains represent potential therapeutic targets for drug discovery. This 27-residue peptide is derived from subdomain 1B of the repetitive domains of calpain, named peptide B27-WT. It is a potent inhibitor of calpain.
Sequence One-Letter Code	DPMSSTYIEELGKREVTIPPKYRELLA
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535156459

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-60844-safety-datasheet.pdf